名称：TF (phospho Ser290)

别名：F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142

Modified：Phosphorylated

描述

coagulation factor III, tissue factor(F3) Homo sapiens This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],

Specification

Entrez GeneID：2152

Swissprot：P13726

Gene Accession：Swiss Prot:P13726
GeneID:2152

WB Predicted band size：40kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：The antiserum was produced against synthesized peptide derived from human Coagulation Factor III around the phosphorylation site of Ser290. AA range:246-295

Formulation：Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application

Application：WB,IHC

WB：1/500 - 1/2000

IHC：1/100 - 1/300

ELISA：1/20000

宿主：Rabbit