名称：STAT3(Ab-705)

别名：APRF; Acute-phase response factor; HIES

Pathway：Jak-STAT signaling pathway

Targets：Disease

描述

Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

文献

Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120.Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804.Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115.Garcia R, et al. (1998) J Biomed Sci. 5: 79-85.Bromberg J F, et al. (1999) Cell. 98: 295-303.

Specification

Entrez GeneID：6774;

Swissprot：P40763

Gene Accession：Swiss-Prot: P40763NCBI Protein: NP_003141.2

WB Predicted band size：88kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around aa.703~707(A-P-Y-L-K) derived from Human STAT3.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF

WB：1/500-1/1000

IHC：1/50-1/100

ICC：1/100-1/200

宿主：Rabbit