名称：iNOS

别名：NITRIC OXIDE SYNTHASE; INDUCIBLE; NITRIC OXIDE SYNTHASE; MACROPHAGE; NOS2A

Targets：FDA approved drug target related

描述

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2

文献

Rachel J. Jones, Am J Physiol Heart Circ Physiol, Jun 2007; 292: H2634 - H2642

Katrin Linker,Nucleic Acids Res., Aug 2005; 33: 4813 - 4827.

Donna-Marie McCafferty,Donna-Marie McCafferty,

Lian-Qun Qiu, J. Am. Soc. Nephrol., Aug 2004; 15: 2066 - 2078.

Specification

Entrez GeneID：4843;

Swissprot：P35228

Gene Accession：Swiss-Prot: P35228NCBI Gene ID: 4843

WB Predicted band size：130kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Synthesized peptide derived from human iNOS.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF

WB：1/500-1/3000

IHC：1/50-1/100

ICC：1/100-1/500

宿主：Rabbit