名称：Cyclin-L1

别名：Cyclin-L; CCNL1;

描述

Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.A. Hamid Boulares, J. Biol. Chem., Aug 1999; 274: 22932. Alessandra Pagano, Am J Physiol Lung Cell Mol Physiol, Jun 2007; 10.1152.Mi Young Kim, Genes & Dev., Sep 2005; 19: 1951 - 1967. Silke S篓鹿sse, Nucleic Acids Res., Feb 2004; 32: 669 - 680.

Specification

Entrez GeneID：57018;

Swissprot：Q9UK58

Gene Accession：Swiss-Prot: Q9UK58NCBI Gene ID: 57018

WB Predicted band size：60kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Synthesized peptide derived from human Cyclin-L1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/3000

IHC：1/50-1/100

宿主：Rabbit