名称：CHSY1

别名：carbohydrate (chondroitin) synthase 1; chondroitin glucuronyltransferase II; chondroitin synthase; CHSS1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1

Targets：Disease

描述

Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.Kitagawa H., J. Biol. Chem. 276:38721-38726(2001).Nagase T., DNA Res. 6:63-70(1999).Clark H.F., Genome Res. 13:2265-2270(2003).

Specification

Entrez GeneID：22856;

Swissprot：Q86X52

Gene Accession：Swiss-Prot: Q86X52NCBI Gene ID: 22856

WB Predicted band size：91kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Synthesized peptide derived from internal of human CHSY1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/3000

IHC：1/50-1/100

宿主：Rabbit