名称：CTDSP1

别名：Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; EC 3.1.3.16; Nuclear LIM interactor-interacting factor 3; NLI-interacting factor 3; NLI-IF

描述

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.Marquet S., Mamm. Genome 11:755-762(2000).Yeo M., J. Biol. Chem. 278:26078-26085(2003).Hillier L.W., Nature 434:724-731(2005)

Specification

Entrez GeneID：58190;

Swissprot：Q9GZU7

Gene Accession：Swiss-Prot: Q9GZU7NCBI Gene ID: 58190

WB Predicted band size：30kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Synthesized peptide derived from N-terminal of human CTDSP1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/3000

IHC：1/50-1/100

宿主：Rabbit