名称：Collagen III

别名：Collagen alpha 1; Collagen alpha 1(III) chain [Precursor];

Targets：FDA approved drug target related

描述

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12

文献

Arja Lamberg, J. Biol. Chem., May 1996; 271: 11988

GW Conrad, J. Cell Biol., Mar 1980; 84: 501

DR Keene, J. Cell Biol., Nov 1987; 105: 2393

HM Wang, J. Histochem. Cytochem., Nov 1980; 28: 1215.

Specification

Entrez GeneID：1281;

Swissprot：P02461

Gene Accession：Swiss-Prot: P02461NCBI Gene ID: 1281

WB Predicted band size：138kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Synthesized peptide derived from internal of human collagen III.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF

WB：1/500-1/1000

IHC：1/50-1/100

ICC：1/100-1/500

宿主：Rabbit