名称：MPRIP

别名：Myosin phosphatase Rho-interacting protein; Rho-interacting protein 3; M-RIP; RIP3; p116Rip

描述

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. UniProtKB P97434Surks H.K., J. Biol. Chem. 278:51484-51493(2003).Koga Y., J. Biol. Chem. 280:4983-4991(2005).Inazawa J., Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.

Specification

Entrez GeneID：23164;

Swissprot：Q6WCQ1

Gene Accession：Swiss-Prot: Q6WCQ1NCBI Gene ID: 23164

WB Predicted band size：117kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse

免疫原：Synthesized peptide derived from internal of human MPRIP.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit