名称：eNOS(Ab-1177)

别名：Constitutive NOS; EC-NOS; ECNOS; NOS3; NOSIII

Pathway：PI3K-Akt signaling pathway

Targets：FDA approved drug target related

描述

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

文献

Fulton, D. et al. (1999) Nature 399, 597-601. Harris, M.B. et al. (2001) J. Biol. Chem. 276, 16587-16591. Thomas, S.R. et al. (2002) J. Biol. Chem. 277, 6017-6024.

Specification

Entrez GeneID：4846;

Swissprot：P29474

Gene Accession：Swiss-Prot: P29474NCBI Protein: NP_000594.2

WB Predicted band size：140kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around aa.1175~1179 (T-Q-S-F-S) derived from Human eNOS.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IF

WB：1/500-1/1000

ICC：1/100-1/200

宿主：Rabbit