名称：Hexokinase-3

别名：Hexokinase-3; EC 2.7.1.1; Hexokinase type III; HK III; HK3

描述

Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3).Furuta H., Genomics 36:206-209(1996).Palma F., Mol. Cell. Biochem. 155:23-29(1996).Sjoeblom T., Science 314:268-274(2006).

Specification

Entrez GeneID：3101;

Swissprot：P52790

Gene Accession：Swiss-Prot: P52790NCBI Gene ID: 3101

WB Predicted band size：99kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Synthesized peptide derived from internal of human Hexokinase-3.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/3000

宿主：Rabbit