名称：ICAM-1(Ab-512)

别名：ICA1; ICAM1;

描述

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

文献

Greenwood J, et al. (2003) J Immunol; 171(4):2099-2108.

Zhou Z, et al. (2005) Eur J Pharmacol; 513(1-2):1-8.

Chen YH, et al. (2001) J Cell Biochem; 82(3):512-521

Specification

Entrez GeneID：3383;

Swissprot：P05362

Gene Accession：Swiss-Prot: P05362NCBI Protein: NP_000192.2

WB Predicted band size：89-92kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit