名称：MAEA

别名：Macrophage erythroblast attacher; Erythroblast macrophage protein; Cell proliferation-inducing gene 5 protein; Lung cancer-related protein 10; HLC-10

描述

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.Ota T., Nat. Genet. 36:40-45(2004).Hanspal M., Blood 92:2940-2950(1998).Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006).

Specification

Entrez GeneID：10296;

Swissprot：Q7L5Y9

Gene Accession：Swiss-Prot: Q7L5Y9NCBI Gene ID: 10296

WB Predicted band size：45kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Synthesized peptide derived from internal of human MAEA.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/3000

宿主：Rabbit