名称：IkB-e(Phospho-Ser22)

别名：I-kappa-B-epsilon; IKBE; IkappaBepsilon; NF-kappa-BIE; NF-kappaB inhibitor epsilon

Modified：Phosphorylated

描述

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.

文献

Shirane M, et al. (1999) J Biol Chem; 274(40): 28169-74

Karin, M. and Ben-Neriah, Y. (2000) Annu. Rev. Immunol. ;18, 621-663.

Chen, Z.J. et al. (1996) Cell; 84, 853-862.

Brown, K. et al. (1995) Science; 267, 1485-1488.

Specification

Entrez GeneID：18037;

Swissprot：O54910

Gene Accession：Swiss-Prot: O54910NCBI Gene ID: 18037NCBI Protein: NP_004547.2

WB Predicted band size：40kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse

免疫原：Peptide sequence around phosphorylation site of serine 22 (I-E-S(p)-L-R) derived from Mouse IkB-蔚.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit