名称：PAK5/6 (Phospho-Ser602/Ser560)

别名：PAK5; PAK 6; kinase PAK6;

Modified：Phosphorylated

描述

This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. Yang F., J. Biol. Chem. 276:15345-15353(2001)Wagner T., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databasesSjoeblom T., Science 314:268-274(2006)

Specification

Entrez GeneID：57144;

Swissprot：Q9P286

Gene Accession：Swiss-Prot#: Q9P286/Q9NQU5; NCBI Gene#: 57144/56924; NCBI Protein#: NP_065074.1.

WB Predicted band size：75kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse

免疫原：Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from Human PAK5/6.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit