名称：Claudin 5 (Phospho-Tyr217)

别名：CLD5; CLDN5; TMDVCF;

Modified：Phosphorylated

描述

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.Sirotkin H., Genomics 42:245-251(1997)Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004)The MGC Project Team; Genome Res. 14:2121-2127(2004)

Specification

Entrez GeneID：7122;

Swissprot：O00501

Gene Accession：Swiss-Prot#: O00501; NCBI Gene#: 7122; NCBI Protein#: NP_001124333.1.

WB Predicted band size：23kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y(p)-V) derived from Human Claudin 5.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit