名称：ANGPT2

别名：Angiopoietin-2, ANG-2, ANGPT2

Pathway：TGF-beta signaling pathway

Pathway：PI3K-Akt signaling pathway

Targets：FDA approved drug target related

描述

The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

Specification

Entrez GeneID：285

Swissprot：O15123

WB Predicted band size：56.9kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat

免疫原：This ANGPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human ANGPT2.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC-P,FCM

WB：1/500-1/2000

IHC：1/100-1/500

FCM：1/25

宿主：Rabbit