名称：MLK1/2 (Phospho-Thr312/266)

别名：M3K9; PRKE1; mixed-lineage protein kinase 1;

Modified：Phosphorylated

描述

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.Durkin J.T., Biochemistry 43:16348-16355(2004)The MGC Project Team; Genome Res. 14:2121-2127(2004)Dorow D.S.,Nature 446:153-158(2007).

Specification

Entrez GeneID：4293;

Swissprot：P80192

Gene Accession：Swiss-Prot#: P80192/Q02779; NCBI Gene#: 4293/4294; NCBI Protein#: NP_001271159.1.

WB Predicted band size：121kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse

免疫原：Peptide sequence around phosphorylation site of threonine 312/266(A-G-T(p)-Y-A) derived from Human MLK1/2.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit