名称：p13Cas (Phospho-Tyr410)

别名：BCAR1; CRKAS; CRK-ASSOCIATED SUBSTRATE;

Modified：Phosphorylated

描述

Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6

Specification

Entrez GeneID：9564;

Swissprot：P56945

Gene Accession：Swiss-Prot#: P56945; NCBI Gene#: 9564; NCBI Protein#: NP_055382.2.

WB Predicted band size：130kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas .

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit