名称：PMCH

别名：Pro-MCH, Neuropeptide-glycine-glutamic acid, NGE, Neuropeptide G-E, Neuropeptide-glutamic acid-isoleucine, NEI, Neuropeptide E-I, Melanin-concentrating hormone, MCH, PMCH, MCH

描述

The melanin-concentrating hormone (MCH) is a cyclic

neuropeptide isolated initially from salmon pituitary gland and

later from rat hypothalamus (summarized by Nahon et al., 1992

[PubMed 1572663]). In mammals, MCH perikarya are confined largely

to the lateral hypothalamus and zona incerta area with extensive

neuronal projections throughout the brain, including the

neurohypophysis. The anatomic distribution suggests a

neurotransmitter or neuromodulator role for MCH in a broad array of

neuronal functions directed toward the regulation of goal-directed

behavior, such as food intake, and general arousal. MCH and 2 other

putative neuropeptides, NEI and NGE, are encoded by the same

precursor and appear colocalized in nerve cells and in many

instances within the projections. The precursor is designated

pro-melanin-concentrating hormone (PMCH).

Specification

Entrez GeneID：5367

Swissprot：P20382

WB Predicted band size：18.7kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat

免疫原：This PMCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of human PMCH.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/1000

宿主：Rabbit