名称：p56Dok-2(Phospho-Tyr299)

别名：DOK2

Modified：Phosphorylated

描述

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

文献

Feng Cong, et,al. (1999) Mol. Cell. Biol ; 19: 8314 - 8325.

Serge Lemay, et,al. (2000) Mol. Cell. Biol ; 20: 2743 - 2754.

Ute Schaeper, et,al.(2000) J. Cell Biol ; 149: 1419.

Miyuki Honma, et,al. (2006) Genes Cells; 11: 143 - 151.

Specification

Entrez GeneID：9046;

Swissprot：O60496

Gene Accession：Swiss-Prot: O60496NCBI Protein: NP_003965.2

WB Predicted band size：56kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF

WB：1/500-1/1000

IHC：1/50-1/100

ICC：1/100-1/200

宿主：Rabbit