名称：PLCg2(phospho-Tyr1217)

别名：PLC-IV; PLC-gamma2; Phospholipase C-gamma-2

Modified：Phosphorylated

Targets：Disease

描述

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

文献

Yue, C. et al. (1998) J. Biol. Chem. 273, 18023-18027. Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225. Margolis, B. et al. (1989) Cell 57, 1101-1107.

Specification

Entrez GeneID：5336;

Swissprot：P16885

Gene Accession：Swiss-Prot: P16885NCBI Protein: NP_002652.2

WB Predicted band size：150kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T) derived from Human PLCg2.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit