名称：INPP5B

别名：Type II inositol 1,5-trisphosphate 5-phosphatase, 75 kDa inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase, 5PTase, INPP5B, OCRL2

描述

Cellular calcium signaling is controlled by the production

of inositol phosphates (IPs) by phospholipase C in response to

extracellular signals. The IP signaling molecules are inactivated

by a family of inositol polyphosphate-5-phosphatases

(5-phosphatases). INPP5B encodes the type II 5-phosphatase. The

protein is localized to the cytosol and mitochondria, and

associates with membranes through an isoprenyl modification near

the C-terminus. Several alternatively spliced transcript variants

of this gene have been described, but the full-length nature of

some of these variants has not been determined. [provided by

RefSeq].

Specification

Entrez GeneID：3633

Swissprot：P32019

WB Predicted band size：112.9kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat

免疫原：This INPP5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 950-979 amino acids from the C-terminal region of human INPP5B.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/1000

宿主：Rabbit