名称：Tip6(Phospho-Ser90)

别名：HTATIP; TI60; Tat-interactive protein-60;

Modified：Phosphorylated

Targets：Disease

描述

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.Kamine J., Virology 216:357-366(1996)Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001)Legube G., Gene 310:161-168(2003)

Specification

Entrez GeneID：10524;

Swissprot：Q92993

Gene Accession：Swiss-Prot#: Q92993; NCBI Gene#: 10524; NCBI Protein#: NP_006379.2.

WB Predicted band size：58kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit