名称：Caveolin 2 (Phospho-Tyr27)

别名：CAV2; Caveolin-2;

Modified：Phosphorylated

描述

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135(1996)Scherer P.E., J. Biol. Chem. 272:29337-29346(1997)Engelman J.A., FEBS Lett. 448:221-230(1999).

Specification

Entrez GeneID：858;

Swissprot：P51636

Gene Accession：Swiss-Prot#: P51636; NCBI Gene#: 858; NCBI Protein#: NP_001224.1.

WB Predicted band size：26kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y(p)-A-D) derived from Human Caveolin 2.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit