名称：Rel(Phospho-Ser503)

别名：C-Rel

Modified：Phosphorylated

描述

The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 (PubMed 18037997)).

文献

Baeuerle, P.A. and Henkel, T. (1994) Annu Rev Immunol 12, 141-79.Baeuerle, P.A. and Baltimore, D. (1996) Cell 87, 13-20.Haskill, S. et al. (1991) Cell 65, 1281-9.Thompson, J.E. et al. (1995) Cell 80, 573-82.

Specification

Entrez GeneID：5966;

Swissprot：Q04864

Gene Accession：Swiss-Prot: Q04864NCBI Protein: NP_002899.1

WB Predicted band size：78kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of serine 503 (T-S-S(p)-D-S) derived from Human Rel.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IF

ICC：1/100-1/200

宿主：Rabbit