名称：KCTD13

别名：BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1, hBACURD1, BTB/POZ domain-containing protein KCTD13, Polymerase delta-interacting protein 1, TNFAIP1-like protein, KCTD13, BACURD1, PDIP1, POLDIP1

Targets：Disease

描述

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.

Specification

Entrez GeneID：253980

Swissprot：Q8WZ19

WB Predicted band size：36.4kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse

免疫原：This KCTD13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-258 amino acids from the C-terminal region of human KCTD13.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/1000

宿主：Rabbit