名称：CD32 (Phospho-Tyr292)

别名：CD32; FCG2; FCG2B,; LY-17; CDW32

Modified：Phosphorylated

描述

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989)Brooks D.G., J. Exp. Med. 170:1369-1385(1989)Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990)

Specification

Entrez GeneID：2213;

Swissprot：P31994

Gene Accession：Swiss-Prot#: P31994 ; NCBI Gene#: 2213; NCBI Protein#: NP_003992.3.

WB Predicted band size：32kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit