名称：YB1 (Phospho-Ser102)

别名：CBF-A; NSEP1; EFI-A; MSY-1; YBX1

Modified：Phosphorylated

描述

YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.Sakura H., Gene 73:499-507(1988)Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326(1988)Kolluri R., Nucleic Acids Res. 19:4771-4771(1991)

Specification

Entrez GeneID：4904;

Swissprot：P67809

Gene Accession：Swiss-Prot#: P67809; NCBI Gene#: 4904; NCBI Protein#: NP_004550.2.

WB Predicted band size：36kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of Serine 102(L-R-S(p)-V-G) derived from Human YB1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit