名称：Gab1(Phospho-Tyr627)

别名：Growth factor receptor bound protein 2-associated protein 1

Modified：Phosphorylated

Targets：Disease

描述

The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

文献

Anders Kallin, et al. (2004) J. Biol. Chem ; 279: 17897 - 17904.Hideto Kameda, et al. (2001) Cell Growth Differ ; 12: 307. Masaki Osawa, et al. (2002) J. Cell Biol ; 158: 773.

Specification

Entrez GeneID：2549;

Swissprot：Q13480

Gene Accession：Swiss-Prot: Q13480NCBI Protein: NP_002030.2

WB Predicted band size：110kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse

免疫原：Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y(p)-L-D) derived from Human Gab1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IF

WB：1/500-1/1000

ICC：1/100-1/200

宿主：Rabbit