名称：PD L1

别名：Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1, B7 homolog 1, B7-H1, CD274

Targets：FDA approved drug target related

描述

Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443, PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).

Specification

Entrez GeneID：29126

Swissprot：Q9NZQ7

WB Predicted band size：33.3kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：This PD L1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human PD L1.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit