名称：PDK1 (Phospho-Tyr9)

别名：hPDK1; PDPK1; mPDK1; PkB kinase;

Pathway：PI3K-Akt signaling pathway

Pathway：mTOR signaling pathway

Modified：Phosphorylated

描述

Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.Alessi D.R., Curr. Biol. 7:261-269(1997)Alessi D.R.,Curr. Biol. 7:776-789(1997)Stephens L.R.,Science 279:710-714(1998)

Specification

Entrez GeneID：5170;

Swissprot：O15530

Gene Accession：Swiss-Prot#: O15530; NCBI Gene#: 5170; NCBI Protein#: NP_002604.1.

WB Predicted band size：63kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 9(A-L-Y(p)-D-A) derived from Human PDK1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit