名称：Connexin 43 (phospho-Ser368)

别名：CX43; CXA1; CXN-43; GJA1;

Modified：Phosphorylated

Targets：Disease

描述

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

文献

Joell L. Solan1, et al. (2003) Cell Science 116: 2203-2211

Satoshi Matsushita, et al. (2006) Histochemistry and Cytochemistry 54 (3): 343-353,

Xiaoyong Bao, et al. (2004) Cell Physiol 286: C647-C654

W. E. I. Li, et al.(1998) European Journal of Neuroscience 10: 2444

Specification

Entrez GeneID：2697;

Swissprot：P17302

Gene Accession：Swiss-Prot: P17302NCBI Protein: NP_000156.1

WB Predicted band size：43kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of serine 368 (R-A-S(p)-S-R) derived from Human Connexin 43.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit