名称：BIM(Phospho-Ser69)

别名：BCL2-like protein 11; BCL2L11; BOD; Bcl-2 related ovarian death protein;

Pathway：PI3K-Akt signaling pathway

Modified：Phosphorylated

描述

Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis

文献

Fukazawa H, et al. (2004) Mol Cancer Ther ; 3(10): 1281-1288Luciano F, et al. (2003) Oncogene ; 22(43): 6785-6793

Specification

Entrez GeneID：10018;

Swissprot：O43521

Gene Accession：Swiss-Prot: O43521NCBI Protein: NP_006529.1

WB Predicted band size：23kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of serine 69 (P-A-S(p)-P-G) derived from Human BIM.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC,IF

IHC：1/50-1/100

ICC：1/100-1/200

宿主：Rabbit