名称：MKK3(Phospho-Ser189)

别名：MAP kinase kinase 3; MAP2K3; MAPK/ERK kinase 3; MAPKK 3; MEK3

Pathway：TGF-beta signaling pathway

Pathway：MAPK signaling pathway

Pathway：Jak-STAT signaling pathway

Modified：Phosphorylated

Targets：Disease

描述

Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.

文献

Wang W, et al. (2002) Mol Cell Biol ; 22(10): 3389-403.

Raingeaud J, et al. (1996) Mol Cell Biol; 16(3): 1247-55.

Specification

Entrez GeneID：5606;

Swissprot：P46734

Gene Accession：Swiss-Prot: P46734NCBI Protein: NP_002747.2

WB Predicted band size：40kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of serine 189 (V-D-S(p)-V-A) derived from Human MKK3.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF

WB：1/500-1/1000

IHC：1/50-1/100

ICC：1/100-1/200

宿主：Rabbit