名称：SHP-1(Phospho-Tyr536)

别名：70Z-SHP; HCP; HCPH; Hematopoietic cell protein-tyrosine phosphatase; PTN6

Pathway：Jak-STAT signaling pathway

Modified：Phosphorylated

描述

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

文献

Migone TS, et al. (1998) Proc Natl Acad Sci USA; 95(7): 3845-3850.

Timms JF, et al.(1998) Mol Cell Biol; 18(7): 3838-3850.

Kanagasundaram V, et al. (1999) Mol Cell Biol; 19(6): 4079-4092.

Hauck CR, et al. (1999) Infect Immun; 67(10): 5490-5494.

Specification

Entrez GeneID：5777;

Swissprot：P29350

Gene Accession：Swiss-Prot: P29350NCBI Protein: NP_002822.2

WB Predicted band size：68kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of tyrosine 536 (S-E-Y(p)-G-N) derived from Human SHP-1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC,IF

IHC：1/50-1/100

ICC：1/100-1/200

宿主：Rabbit