名称：MCOLN1

别名：Mucolipin-1, MG-2, Mucolipidin, MCOLN1, ML4

Targets：Disease

描述

This gene encodes a memberof the transient receptor

potential (TRP) cation channel gene family. The transmembrane

protein localizes to intracellular vesicular membranes including

lysosomes, and functions in the late endocytic pathway and in the

regulation of lysosomal exocytosis. The channel is permeable to

Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes

in Ca(2+) concentration. Mutations in this gene result in

mucolipidosis type IV.

Specification

Entrez GeneID：57192

Swissprot：Q9GZU1

WB Predicted band size：65.0kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：This MCOLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/2000

宿主：Rabbit