名称：AIRE

别名：Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED

Targets：Disease

描述

This gene encodes a transcriptional regulator that forms

nuclear bodies and interacts with the transcriptional coactivator

CBP. At least three splice variant mRNAs products have been

described including one which results in a premature stop codon and

a transcript predicted to be a candidate for nuclear-mediated decay

(NMD). Defects in this gene cause the rare autosomal-recessive

systemic autoimmune disease termed autoimmune

polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Specification

Entrez GeneID：326

Swissprot：O43918

WB Predicted band size：57.7kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat

免疫原：This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/2000

宿主：Rabbit