名称：MYT1 (Phospho-Ser83)

别名：PMYT1; PKMYT1; MYT1 kinase;

Modified：Phosphorylated

描述

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Booher R.N., J. Biol. Chem. 272:22300-22306(1997)Liu F., Mol. Cell. Biol. 17:571-583(1997)Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006)

Specification

Entrez GeneID：9088;

Swissprot：Q99640

Gene Accession：Swiss-Prot#: Q99640; NCBI Gene#: 9088; NCBI Protein#: XP_006721039.1.

WB Predicted band size：54kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit