名称：Zap-70(Phospho-Tyr493)

别名：70 kDa zeta-associated protein; SRK; Syk-related tyrosine kinase; ZA70; ZAP-70

Modified：Phosphorylated

Targets：Disease

描述

Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not.

文献

Chan AC, et al. (1995) EMBO J; 14(11): 2499-2508Kong G, et al. (1996) Mol Cell Biol; 16(9): 5026-5035Salomon AR, et al. (2003)Proc Natl Acad Sci U S A; 100(2): 443-448

Specification

Entrez GeneID：7535;

Swissprot：P43403

Gene Accession：Swiss-Prot: P43403 NCBI Protein: NP _001070.2

WB Predicted band size：70kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of tyrosine 493 (S-Y-Y(p)-T-A) derived from Human Zap-70.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit