名称：a-catenin(Phospho-Ser641)

别名：Cadherin-associated protein; Alpha E-catenin; NY-REN-13 antigen

Modified：Phosphorylated

描述

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.

文献

Hwang, S.G. et al. (2005) J. Biol. Chem. 280, 12758-12765

Drees, F. et al. (2005) Cell 123, 903-915.

Yamada, S. et al. (2005) Cell 123, 889-901.

Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.

Specification

Entrez GeneID：1495;

Swissprot：P35221

Gene Accession：Swiss-Prot: P35221NCBI Protein: NP_001894.2

WB Predicted band size：100kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse

免疫原：Peptide sequence around phosphorylation site of serine 641 (D-D-S(p)-D-F) derived from Human a-catenin.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit