名称：CtBP1 (Phospho-Ser422)

别名：CTBP; C-terminal binding protein 1; EC 1.1.1;

Modified：Phosphorylated

Targets：Disease

描述

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995)Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999)The MGC Project Team, Genome Res. 14:2121-2127(2004)

Specification

Entrez GeneID：1487;

Swissprot：Q13363

Gene Accession：Swiss-Prot#: Q13363; NCBI Gene#: 1487; NCBI Protein#: NP_001319.1.

WB Predicted band size：48kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit