名称：Vinculin (Phospho-Tyr822)

别名：Vinculin;

Modified：Phosphorylated

Targets：Disease

描述

Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion

文献

Subauste MC, et al. (2004) J Cell Biol 165, 371-81

Olsen JV, et al. (2010) Sci Signal 3, ra3

J?rgensen C, et al. (2009) Science 326, 1502-9

Specification

Entrez GeneID：7414;

Swissprot：P18206

Gene Accession：Swiss-Prot#: P18206; NCBI Gene#: 7414; NCBI Protein#: NP_003364.1

WB Predicted band size：123kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of Tyrosine 822 (S-G-Y(p)-R-I) derived from Human Vinculin.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit