名称：Mouse Txnip

别名：Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1

描述

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

Specification

Entrez GeneID：56338

Swissprot：Q8BG60

WB Predicted band size：44.4kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat

免疫原：This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC-P

WB：1/2000

IHC：1/100

宿主：Rabbit