名称：EPHA3/4/5 (Phospho-Tyr779/833)

别名：EPA3; ETK; HEK; MEK4; REK

Modified：Phosphorylated

描述

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands

文献

Wicks I.P., Proc. Natl. Acad. Sci. U.S.A. 89:1611-1615(1992)

Chiari R., Cancer Res. 60:4855-4863(2000)

Boyd A.W., J. Biol. Chem. 267:3262-3267(1992).

Specification

Entrez GeneID：2042;

Swissprot：P29320

Gene Accession：Swiss-Prot#: P29320/54764/54756; NCBI Gene#: 2042/2043; NCBI Protein#: NP_004429.1.

WB Predicted band size：110kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y(p)-T-T)/(A-A-Y(p)-T-T) derived from Human EPHA3/4/5.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit