名称：iNOS (Phospho-Tyr151)

别名：HEP-NOS; NOS2; inducible;

Modified：Phosphorylated

Targets：FDA approved drug target related

描述

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993)Sherman P.A., Biochemistry 32:11600-11605(1993)Charles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993)

Specification

Entrez GeneID：4843;

Swissprot：P35228

Gene Accession：Swiss-Prot#: P35228; NCBI Gene#: 4843; NCBI Protein#: NP_000616.3.

WB Predicted band size：131kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 151(Q-Y-Y(p)-G-S) derived from Human iNOS .

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：IHC

IHC：1/50-1/100

宿主：Rabbit