名称：Myc(Phospho-Ser373)

别名：c-myc

Pathway：PI3K-Akt signaling pathway

Pathway：MAPK signaling pathway

Modified：Phosphorylated

描述

Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

文献

Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702.Blackwood E M, et al. (1991) Science. 251:1211-1217.Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.

Specification

Entrez GeneID：4609;

Swissprot：P01106

Gene Accession：Swiss-Prot: P01106NCBI Protein: NP_002458.2

WB Predicted band size：60kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of serine 373 derived from Human Myc.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit