名称：Histone H3 (Tri-Methyl-Lys27)

别名：H3/a, H3/c, H3/d, H3/f, H3/h

Modified：Methylated

Targets：Disease

描述

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specification

Entrez GeneID：8350;8351;8352;8353;8354;8355;8356;8357;8358;8968;

Swissprot：P68431

Gene Accession：Swiss-Prot#:P68431 NCBI Gene#:8351 NCBI Protein#:NP_003521.2

WB Predicted band size：17kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around Tri-Methylation site of lysine 27(A-R-K(tri-methyl)-S-A) derived from Human Histone H3.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF

WB：1/500-1/1000

IHC：1/50-1/100

ICC：1/100-1/200

宿主：Rabbit