名称：SHP-2(Phospho-Tyr542)

别名：PTN11; PTP-1D; PTP-2C; PTP2C; PTPN11

Pathway：Jak-STAT signaling pathway

Modified：Phosphorylated

Targets：Disease

描述

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

文献

Ferjoux G, et al. (2003) Mol Biol Cell. 2003; 14(9): 3911-3928.

Shi ZQ, et al. (2000) Mol Cell Biol. 20(5): 1526-1536.

Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A ; 96(17): 9677-9682

Manes S, et al. (1999) Mol Cell Biol. 19(4): 3125-3135.

Oh ES, et al. (1999) Mol Cell Biol; 19(4): 3205-3215.

Specification

Entrez GeneID：5781;

Swissprot：Q06124

Gene Accession：Swiss-Prot: Q06124NCBI Protein: NP_002825.3

WB Predicted band size：72kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Peptide sequence around phosphorylation site of tyrosine 542 (H-E-Y(p)-T-N) derived from Human SHP-2.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit