名称：CXCR4(N-term)

别名：C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, Lipopolysaccharide-associated protein 3, LAP-3, LPS-associated protein 3, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD184, CXCR4

Pathway：Jak-STAT signaling pathway

Targets：FDA approved drug target related

描述

This gene encodes a CXC chemokine receptor specific for

stromal cell-derived factor-1. The protein has 7 transmembrane

regions and is located on the cell surface. It acts with the CD4

protein to support HIV entry into cells and is also highly

expressed in breast cancer cells. Mutations in this gene have been

associated with WHIM (warts, hypogammaglobulinemia, infections, and

myelokathexis) syndrome. Alternate transcriptional splice variants,

encoding different isoforms, have been characterized. [provided by

RefSeq].

Specification

Entrez GeneID：7852

Swissprot：P61073

WB Predicted band size：39.7kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat

免疫原：This CXCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CXCR4.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/1000-1/2000

宿主：Rabbit