名称：CK-1α (Phospho-Tyr294)

别名：KC1A; CKI-alpha; CSNK1A1; alpha isoform; Casein kinase I

Pathway：Wnt signaling pathway

Modified：Phosphorylated

描述

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349:307-312(1994)Fish K.J., J. Biol. Chem. 270:14875-14883(1995)Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases

Specification

Entrez GeneID：1452;

Swissprot：P48729

Gene Accession：Swiss-Prot#: P48729/Q8N752; NCBI Gene#: 1452/122011; NCBI Protein#: NP_001883.4.

WB Predicted band size：37kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y(p)-T-F) derived from Human CK-1α.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit